INFORMATION & LABORATORY RESEARCH PURPOSES ONLY

Metabolic signalling

Survodutide

Dual glucagon / GLP-1 receptor agonistHuman clinical trial

What is it?

Survodutide is a synthetic peptide studied for glucagon and GLP-1 receptor activity. It has been investigated in obesity and metabolic dysfunction-associated steatohepatitis (MASH), a form of inflammatory fatty-liver disease. It is a distinct molecule from mazdutide despite a similar receptor pairing.

How it is studied

The two receptor activities link appetite and glucose signalling with glucagon-related metabolism. Liver research asks whether changes in these pathways affect inflammation and tissue injury. A mechanism provides a hypothesis, not a guarantee of liver recovery or weight loss.

What the evidence shows

A randomised phase 2 trial published in 2024 evaluated survodutide in MASH and fibrosis. It assessed defined liver outcomes under controlled conditions. Disease-specific findings should be interpreted separately from body-weight outcomes or performance claims.

Limitations & safety context

Gastrointestinal adverse events and treatment discontinuation are relevant to the trial interpretation. Results for supervised participants with diagnosed liver disease do not justify personal use of a catalogue vial. Exact molecular identity and formulation must be confirmed independently of the SUR10 code.

Listed specifications

ReferenceListed contents
SUR1010 mg

Source-document quantities, not doses or a confirmation of stock. Identity, purity, component composition and suitability require separate documentation.

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Research information only. No dosing, administration or treatment advice.