Neuropeptides
Pinealon
What is it?
Pinealon is a synthetic tripeptide with the sequence glutamate–aspartate–arginine, abbreviated EDR. It is studied in cell-stress and neurobiological contexts. It is not melatonin and should not be confused with a pineal-hormone preparation.
How it is studied
Research has examined reactive oxygen species, cell viability and proliferation. Reactive oxygen species are chemical signals as well as potential contributors to damage; reducing an assay measurement does not automatically establish a beneficial organism-level effect.
What the evidence shows
A 2011 experimental paper assessed Pinealon in cerebellar granule cells, neutrophils and PC12 cells under oxidative stress. Different endpoints changed at different concentrations. This is mechanistic cell evidence rather than a demonstration of improved cognition or longer life in people.
Limitations & safety context
Cell-cycle effects and model-specific responses make simple “neuroprotection” claims incomplete. Sequence identity and assay conditions are essential for comparing results. The attachment’s 5 mg, 10 mg and 20 mg entries do not establish clinical efficacy or safety.
Listed specifications
| Reference | Listed contents |
|---|---|
| PI5 | 5 mg |
| PI10 | 10 mg |
| PI20 | 20 mg |
Source-document quantities, not doses or a confirmation of stock. Identity, purity, component composition and suitability require separate documentation.
Research information only. No dosing, administration or treatment advice.